The main problem of diseases of the digestive system on livestock farms is the low adaptive capacity of young animal body. Subsequently, a large percentage of dyspepsia incidence is revealed. Violations of technologies for raising young animals result in a sharp transition in feeding and provoke the appearance of nutritional dyspepsia. Changes can be observed not only in the clinical status of calves, but in the hematological profile. Specialists primarily analyze the results of a general blood test, which does not reflect an objective picture of the disease. It would be more correct to consider the dynamics of integral blood indices. The article presents the results of the analysis of leukocyte intoxication index (Kalf-Kalif), modified leukocyte intoxication index (Reis), leukocyte shift index (Yabluchansky), nuclear index (Dashtayants), adaptation index (Garkavi), allergization index (Kobets and co-authors). This study makes it possible to fully determine the degree of intoxication and allergization, the level of shift in the leukocyte formula and adaptation of the body. At the beginning of the development of the disease, calves exhibit minor intoxication, an allergic reaction and tissue degradation develop. The data obtained make it possible to select a treatment regimen that includes enterosorbents. Integrating of sorption drugs into the main treatment regimen lead to normalization of hematopoietic processes and integral hematological indices. More over, improvement of adaptive potential, faster recovery of the body of calves after illness, and reduction of intoxication are noted.

Voronova Kristina A., Kletikova Lyudmila V.

1. Sychyov S. M., Belchenko S. A., Malyavko G. P., Dronov A. V., Osipov A. A. Dynamics of development of the agro-industrial complex (on the example of the Bryansk region – 2022, 2023). Vestnik Bryanskoj gosudarstvennoj sel'skohozyajstvennoj akademii, 2023;1:3–9 (in Russ.) DOI: 10.52691/2500-2651-2023-95-1-3-9.
2. Gorelik A. S. Physiological rationale for the use of "Albitbio" in dairy calves to correct metabolic processes, increase safety and growth rate. Extended abstract of candidate’s thesis. Kazan', 2018, 20 p. (in Russ.).
3. Spiridonov A. G. Gastro-intestinal diseases etiology in calves and piglets on the farms of Middle Volga region and Preduralye. Uchenye zapiski Kazanskogo gosudarstvennogo veterinarnogo instituta imeni N. E. Baumana, 2011;206:200–204 (in Russ.).
4. Koryakina L. P., Borisov N. I. Physiological and biochemical status features of blood of calves during early postnatal ontogenesis. Izvestiya Sankt-Peterburgskogo gosudarstvennogo agrarnogo universiteta, 2016;43:127–131 (in Russ.).
5. Kalinkina Yu. V., Fedorin A. A., Kalyuzhny I. I., Chulenev A. S. The prevalence and factors contributing to the incidence of neonatal gastroenteritis in newborn calves. Agrarnyi nauchnyi zhurnal, 2023;2:86–90 (in Russ.). DOI: 10.28983/asj.y2022i2pp86-90.
6. Naumov N., Naumov M. A method of prevention of diarrhea syndrome in newborn calves. Veterinariya sel'skokhozyaistvennykh zhivotnykh, 2021;12:43–46 (in Russ.).
7. Quigley J. D., Kost C. J., Wolfe T. M. Absorption of protein IgG and in calves fed a colostrum supplement or replacer. Journal of Dairy Science, 2002;85:1243–1248. DOI: 10.3168/jds.S0022-0302(02)74188-X.
8. Topuria L. Yu., Topuria G. M. Functional state of the body of young calves with gastrointestinal pathology. Izvestiya Orenburgskogo gosudarstvennogo agrarnogo universiteta, 2023;1(99):193–197 (in Russ.). DOI: 10.37670/2073-0853-2023-99-1-193-197.
9. Rogaleva E. V., Semenenko M. P., Kuzminova E. V., Abramov A. A., Semenenko K. A. Treatment of functional disorders of the gastrointestinal tract of calves with a complex drug based on montmorillonite. Uchenye zapiski Kazanskogo gosudarstvennogo veterinarnogo instituta imeni N. E. Baumana, 2020;242:144–149 (in Russ.). DOI: 10.31588/2413-4201-1883-242-2-144-149.
10. Voronova K. A., Kletikova L. V. Assessment of the adaptive potential of calves at the first signs of nutritional dyspepsia. Agrarnyi Vestnik Verkhnevolzh'ya, 2022;3(40):45–50 (in Russ.). DOI: 10.35523/2307-5872-2022-40-3-45–50.
11. Medvedeva M. A. Clinical veterinary laboratory diagnostics. Handbook for veterinarians, Moscow, Akvarium-Print, 2008. 416 p. (in Russ.).