A short peptide with a molecular weight of 0.9 kDa was isolated from the pepsin hydrolysate of cow colostrum, consisting of 8 amino acids with the following sequence: leucine, arginine, glutamic acid, glycine, isoleucine, lysine, asparagine, lysine. According to the Protein NCBI database, the resulting peptide is unknown and its biological effect has not been investigated. It is assumed that the peptide has antiviral properties. A synthesized peptide analog of the natural one was used for the studies. As a result of the studies, it was found that the synthesized peptide has pronounced antiviral properties at a dose of 390 mcg/ml of medium. The number of transmitted lentiviral particles into the cell genome and the penetration of the virus through the cell membrane in the presence of the peptide decreased by 53.6 and 58.4 %. The ice cream "Vanilla ice cream 15 %" enriched with a peptide with antiviral properties was developed. The resulting ice cream met the requirements of GOST 31457–2012 "Milk ice cream, cream".

Merzlyakova Nataliya V., Tikhonov Sergey L., Tikhonova Natalya V.

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