This paper discusses the effect of the use of dihydroquercetin in the feeding of rearing young laying hens aged from 1 to 21 weeks of the Highsex Brown cross in the conditions of the Novoivanovskaya poultry farm of the Svobodnensky district. The duration of the experiment was 150 days. 4 groups of chickens at the age of one week were selected according to the analogues pair’s method, 46 animals each. The control group received the main diet adopted in the farm, and the diet of I, II, III experimental groups included the addition of dihydroquercetin (from one to 8 weeks in the amount of 1; 2; 3 mg per head per day; from 9 to 16 weeks – 2; 3; 4 mg per day; from 17 to 21 weeks – 3; 4; 5 mg per head per day). The diet of the animals was balanced and met the requirements of the All-Russian Scientific Research and Technological Institute of Poultry Farming. As a result of the research, it turned out that the inclusion of dihydroquercetin in the diet of animals has a positive effect on the increase in the live weight of the experimental bird, helps to reduce feed consumption, and increases its palatability. Blood tests and measurements of experimental animals did not reveal a negative effect on their growth, development and health.

Sharvadze Roini L., Penzin  Andrey A.

1. Grab A. V. Polnotsennoe kormlenie zhivotnykh [Complete feeding of animals]. Proceedings from 2-ya Nauchno-prakticheskaya konferenciya – 2nd Scientific and Practical Conference. (PP. 301–306), Stavropol, AGRUS, 2017 (in Russ.).
2. Skrebneva K. S. Polnotsennoe kormlenie – zalog zdorovogo sostoyaniya i vysokikh produktivnykh kachestv zhivotnykh [Complete feeding is the key to a healthy state and high productive qualities of animals]. Proceedings from Actual issues of energy in the agro-industrial complex: Vserossijskaya nauchno-prakticheskaya konferenciya s mezhdunarodnym uchastiem – All-Russian Scientific and Practical Conference with International Participation. (PP. 149–151), Blagoveshchensk, Dal'nevostochnyi gosudarstvennyi agrarnyi universitet, 2019 (in Russ.).
3. Bezzubtsev A. V., Ermolenko G. A., Romanov V. S., Gavrilova T. V. Proizvodstvo i ispol'zovanie spiruliny v kormosmesyakh kur-nesushek v ZAO "Irtyshskaya ptitsefabrika" Omskoi oblasti [Production and use of spirulina in feed mixtures of laying hens in CJSC "Irtysh poultry farm" of the Omsk region). Proceedings from Dostizheniya i aktual'nye problemy zhivotnovodstva Zapadnoi Sibiri – Achievements and actual problems of animal husbandry in Western Siberia. (PP. 104–110), Omsk, Omskij gosudarstvennyj agrarnyj universitet, 2000 (in Russ.).
4. Sistema vedeniya zhivotnovodstva v Amurskoj oblasti: proizvodstvenno-prakticheskij spravochnik [The system of animal husbandry in the Amur region: a production and practical guide], Blagoveshchensk, Dal'nevostochnyi gosudarstvennyi agrarnyi universitet, 2020, 452 p. (in Russ.).
5. Mahfuz S., Shang Q., Piao X. Phenolic compounds as natural feed additives in poultry and swine diets: a review. Journal of Animal Science and Biotechnology, 2021; 12: 48.
6. Weidmann A. E. Dihydroquercetin: More than Just an Impurity? European Journal of Pharmacology, 2012; 684: 19.
7. Iskender H., Yenice G., Dokumacioglu E., Kaynar O., Hayirli A., Kaya. A. The effects of dietary flavonoid supplementation on the antioxidant status of laying hens. Brazilian Journal of Poultry Science, 2016; 18: 663–668.
8. Foley S. L., Lynne A. M., Nayak R. Salmonella challenges: prevalence in swine and poultry and potential pathogenicity of such isolates. Journal of Animal Science, 2008; 86: E149–E162.
9. Fazilatun N. Nornisah M., Zhari I. Superoxide radical scavenging properties of extracts and flavonoids isolated from the leaves of Blumea balsamifera. Pharmaceutical Biology, 2004;42: 404–408.
10. Savvin A. V. Ispol'zovanie antiokislitelya digidrokvertsetina v sostave molochnykh produktov [The use of the antioxidant dihydroquercetin in the composition of dairy products]. Pererabotka moloka. – Milk processing, 2006; 7: 12–13 (in Russ.).
11. Kamboh A. A., Arain M. A., Mughal M. J., Zaman A., Arain Z. M., Soomro A. H. Flavonoids: health promoting phytochemicals for animal production: a review. Journal of Animal Health and Production, 2015, 3: 6.
12. Pirgozliev V. R., Mansbridge S. C., Westbrook C. A., Woods C. A., Rose S. P., Whiting I. M. [et al.]. Feeding dihydroquercetin and vitamin E to broiler chickens reared at standard and high ambient temperatures. Archives of Animal Nutrition, 2020; 74: 496.
13. Plotnikov M. B., Tyukovnina N. A., Plotnikova T. M. Lekarstvennye preparaty na osnove dikvertina [Medicinal preparations based on diquertin], Tomsk, Tomskij gosudarstvennyj universitet, 2005, 208 p. (in Russ.).
14. Uminskii A. A., Khavsteen B. Kh., Bakaneva V. F. Biokhimiya flavonoidov i ikh znachenie v meditsine [Biochemistry of flavonoids and their significance in medicine], Pushchino, Foton-vek, 2007, 264 p. (in Russ.).
15. Babkin V. A. Promyshlennoe proizvodstvo meditsinskikh preparatov i biologicheski aktivnykh dobavok iz drevesiny i kory listvennitsy [Industrial production of medical preparations and biologically active additives from timber and larch bark]. Proceedings from Fundamental science for the development of chemical and chemical-pharmaceutical industry: II Nauchnoprakticheskaya konferenciya – II Scientific and Practical Conference. (PP. 85–88), Perm', Permskij gosudarstvennyj universitet, 2004 (in Russ.).
16. Kolhir V. K., Bykov V., Baginskaya A. I., Sokolov S. I., Glazova N. G., Leskova T. E. Antioxidant activity of a dihydroquercetin isolated from Larixgmelinii (Rupr.) Wood. Phytotherapy research, 1996; 10: 478–482.